Item Type | Name |
Concept
|
Action Potentials
|
Concept
|
Dependovirus
|
Concept
|
Acclimatization
|
Concept
|
Allosteric Site
|
Concept
|
Sodium-Potassium-Exchanging ATPase
|
Concept
|
Biocompatible Materials
|
Concept
|
Amino Acid Sequence
|
Concept
|
Animals
|
Concept
|
Animals, Newborn
|
Concept
|
Anura
|
Concept
|
Arginine
|
Concept
|
Base Sequence
|
Concept
|
Binding Sites
|
Concept
|
Electricity
|
Concept
|
Cell Separation
|
Concept
|
Chelating Agents
|
Concept
|
Cnidarian Venoms
|
Concept
|
Cold Temperature
|
Concept
|
Cricetulus
|
Concept
|
Cholesterol
|
Concept
|
Ciona intestinalis
|
Concept
|
Dimethylpolysiloxanes
|
Concept
|
Dose-Response Relationship, Radiation
|
Concept
|
Drosophila
|
Concept
|
Electrophysiology
|
Concept
|
Electric Conductivity
|
Concept
|
Models, Chemical
|
Concept
|
Fluorescence
|
Concept
|
Neural Conduction
|
Concept
|
Gold
|
Concept
|
Hippocampus
|
Concept
|
Ouabain
|
Concept
|
Liposomes
|
Concept
|
Flow Cytometry
|
Concept
|
Fluorometry
|
Concept
|
Graphite
|
Concept
|
Light
|
Concept
|
Luminescent Measurements
|
Concept
|
Magnesium
|
Concept
|
Melanins
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Laboratories
|
Concept
|
Models, Molecular
|
Concept
|
Picrates
|
Concept
|
Macaca mulatta
|
Concept
|
Models, Theoretical
|
Concept
|
Markov Chains
|
Concept
|
Monosaccharide Transport Proteins
|
Concept
|
Monte Carlo Method
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Motor Neurons
|
Concept
|
Cricetinae
|
Concept
|
Hot Temperature
|
Concept
|
Ion Channels
|
Concept
|
Isoleucine
|
Concept
|
Neurophysiology
|
Concept
|
Synaptic Transmission
|
Concept
|
Lipid Bilayers
|
Concept
|
Phenylurea Compounds
|
Concept
|
Muscle Proteins
|
Concept
|
Polymers
|
Concept
|
Potassium
|
Concept
|
Protein Conformation
|
Concept
|
Sea Anemones
|
Concept
|
Rana pipiens
|
Concept
|
Xenopus
|
Concept
|
Potassium Channels
|
Concept
|
Radio Waves
|
Concept
|
Scorpions
|
Concept
|
Sodium
|
Concept
|
Silicones
|
Concept
|
Humans
|
Concept
|
Terbium
|
Concept
|
United States
|
Concept
|
United States Food and Drug Administration
|
Concept
|
Tryptophan
|
Concept
|
Xenopus laevis
|
Concept
|
Calcium Channels
|
Concept
|
Ultraviolet Rays
|
Concept
|
X-Rays
|
Concept
|
Sodium Channels
|
Concept
|
Locomotion
|
Concept
|
Nicotinic Agonists
|
Concept
|
Insect Proteins
|
Concept
|
Tyrosine
|
Concept
|
Water
|
Concept
|
Protein Structure, Quaternary
|
Concept
|
4-Aminopyridine
|
Concept
|
Mutagenesis
|
Concept
|
Microinjections
|
Concept
|
Mitochondria
|
Concept
|
Molecular Probes
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Mutagenesis, Site-Directed
|
Concept
|
Myocardium
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Anisotropy
|
Concept
|
Dermoscopy
|
Concept
|
Patch-Clamp Techniques
|
Concept
|
DNA, Complementary
|
Concept
|
Loligo
|
Concept
|
Clione
|
Concept
|
Muscle, Skeletal
|
Concept
|
Sodium-Glucose Transporter 1
|
Concept
|
Kv1.1 Potassium Channel
|
Concept
|
Kv1.3 Potassium Channel
|
Concept
|
Calcium Signaling
|
Concept
|
Mutation, Missense
|
Concept
|
Electric Capacitance
|
Concept
|
Sodium Channel Blockers
|
Concept
|
Lanthanoid Series Elements
|
Concept
|
Drosophila Proteins
|
Concept
|
Neurotoxins
|
Concept
|
Protein Structure, Secondary
|
Concept
|
Receptors, G-Protein-Coupled
|
Concept
|
Microfluidic Analytical Techniques
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Decapodiformes
|
Concept
|
Shaker Superfamily of Potassium Channels
|
Concept
|
Ether-A-Go-Go Potassium Channels
|
Concept
|
COS Cells
|
Concept
|
Muscarinic Agonists
|
Concept
|
Amino Acid Substitution
|
Concept
|
Potassium Channels, Inwardly Rectifying
|
Concept
|
Mice
|
Concept
|
Receptors, Nicotinic
|
Concept
|
Metal Nanoparticles
|
Concept
|
RNA, Messenger
|
Concept
|
Mechanotransduction, Cellular
|
Concept
|
Silicon
|
Concept
|
Spectrometry, Fluorescence
|
Concept
|
Spinocerebellar Degenerations
|
Concept
|
Swimming
|
Concept
|
Receptor, Muscarinic M2
|
Concept
|
Rats
|
Concept
|
Static Electricity
|
Concept
|
Tropical Climate
|
Concept
|
Temperature
|
Concept
|
Models, Statistical
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
|
Concept
|
PTEN Phosphohydrolase
|
Concept
|
Molecular Imaging
|
Concept
|
Gene Knockdown Techniques
|
Concept
|
Cation Transport Proteins
|
Concept
|
History, 20th Century
|
Concept
|
KCNQ1 Potassium Channel
|
Concept
|
KCNQ2 Potassium Channel
|
Concept
|
Kv1.2 Potassium Channel
|
Concept
|
Nanoparticles
|
Concept
|
Nanowires
|
Concept
|
Nanotechnology
|
Concept
|
KCNQ Potassium Channels
|
Concept
|
Shaw Potassium Channels
|
Concept
|
Voltage-Sensitive Dye Imaging
|
Concept
|
Axons
|
Concept
|
Calcium
|
Concept
|
Chickens
|
Concept
|
Climate
|
Concept
|
Disease Models, Animal
|
Concept
|
Electrochemistry
|
Concept
|
Fluorescent Dyes
|
Concept
|
Heart Rate
|
Concept
|
Infrared Rays
|
Concept
|
Lymphocytes
|
Concept
|
Lysine
|
Concept
|
Membrane Potentials
|
Concept
|
Models, Biological
|
Concept
|
Models, Neurological
|
Concept
|
Movement
|
Concept
|
Protons
|
Concept
|
Staining and Labeling
|
Concept
|
Conserved Sequence
|
Concept
|
DNA Primers
|
Concept
|
Potassium Channels, Voltage-Gated
|
Concept
|
Fluorescence Resonance Energy Transfer
|
Concept
|
Receptor, Muscarinic M1
|
Concept
|
Microscopy, Electron, Transmission
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channels
|
Concept
|
Large-Conductance Calcium-Activated Potassium Channel beta Subunits
|
Concept
|
Intermediate-Conductance Calcium-Activated Potassium Channels
|
Concept
|
Optical Phenomena
|
Concept
|
Molecular Dynamics Simulation
|
Academic Article
|
Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.
|
Academic Article
|
Structural biology. Force and voltage sensors in one structure.
|
Academic Article
|
Voltage sensor movements.
|
Academic Article
|
Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements.
|
Academic Article
|
Detecting rearrangements of shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells.
|
Academic Article
|
Extensive editing of mRNAs for the squid delayed rectifier K+ channel regulates subunit tetramerization.
|
Academic Article
|
Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter.
|
Academic Article
|
A fluorometric approach to local electric field measurements in a voltage-gated ion channel.
|
Academic Article
|
The voltage-sensor structure in a voltage-gated channel.
|
Academic Article
|
RNA editing of a human potassium channel modifies its inactivation.
|
Academic Article
|
beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel.
|
Academic Article
|
Voltage-gated ion channels.
|
Academic Article
|
Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer.
|
Academic Article
|
Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement.
|
Academic Article
|
A proton pore in a potassium channel voltage sensor reveals a focused electric field.
|
Academic Article
|
Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor.
|
Academic Article
|
A common pathway for charge transport through voltage-sensing domains.
|
Academic Article
|
S4-based voltage sensors have three major conformations.
|
Academic Article
|
Fluorescence detection of the movement of single KcsA subunits reveals cooperativity.
|
Academic Article
|
Gating of the bacterial sodium channel, NaChBac: voltage-dependent charge movement and gating currents.
|
Academic Article
|
The origin of subconductance levels in voltage-gated K+ channels.
|
Academic Article
|
Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics.
|
Academic Article
|
A single charged voltage sensor is capable of gating the Shaker K+ channel.
|
Academic Article
|
Coupling between the voltage-sensing and phosphatase domains of Ci-VSP.
|
Academic Article
|
Gating currents from neuronal K(V)7.4 channels: general features and correlation with the ionic conductance.
|
Academic Article
|
Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential.
|
Academic Article
|
How membrane proteins sense voltage.
|
Academic Article
|
Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid.
|
Academic Article
|
Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain.
|
Academic Article
|
Tuning the voltage-sensor motion with a single residue.
|
Academic Article
|
An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
|
Academic Article
|
The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers.
|
Academic Article
|
In search of a consensus model of the resting state of a voltage-sensing domain.
|
Academic Article
|
Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer.
|
Academic Article
|
The action potential: from voltage-gated conductances to molecular structures.
|
Academic Article
|
Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels.
|
Academic Article
|
Charge movement of a voltage-sensitive fluorescent protein.
|
Academic Article
|
Intermediate state trapping of a voltage sensor.
|
Academic Article
|
The voltage sensor and the gate in ion channels.
|
Academic Article
|
Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
|
Academic Article
|
Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor.
|
Academic Article
|
IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits.
|
Academic Article
|
Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels.
|
Academic Article
|
Thermal mechanisms of millimeter wave stimulation of excitable cells.
|
Academic Article
|
Probing a-3(10) transitions in a voltage-sensing S4 helix.
|
Academic Article
|
Sensing charges of the Ciona intestinalis voltage-sensing phosphatase.
|
Academic Article
|
The gating charge should not be estimated by fitting a two-state model to a Q-V curve.
|
Academic Article
|
S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel.
|
Academic Article
|
Total chemical synthesis of biologically active fluorescent dye-labeled Ts1 toxin.
|
Academic Article
|
Moving gating charges through the gating pore in a Kv channel voltage sensor.
|
Academic Article
|
Functional Site-Directed Fluorometry.
|
Academic Article
|
Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator.
|
Academic Article
|
ß1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel.
|
Academic Article
|
Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin.
|
Academic Article
|
A Novel Voltage Sensor in the Orthosteric Binding Site of the M2 Muscarinic Receptor.
|
Academic Article
|
Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin.
|
Academic Article
|
Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET.
|
Academic Article
|
Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit.
|
Academic Article
|
Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape.
|
Academic Article
|
Biophysical Characterization of Genetically Encoded Voltage Sensor ASAP1: Dynamic Range Improvement.
|
Academic Article
|
Gating currents.
|
Academic Article
|
Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels.
|
Academic Article
|
Nav channel binder containing a specific conjugation-site based on a low toxicity ß-scorpion toxin.
|
Academic Article
|
Continuum Gating Current Models Computed with Consistent Interactions.
|
Academic Article
|
Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker.
|
Academic Article
|
Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K+ channels.
|
Academic Article
|
Gating current noise produced by Brownian models of a voltage sensor.
|
Academic Article
|
Tracking the movement of discrete gating charges in a voltage-gated potassium channel.
|
Academic Article
|
Optocapacitance: physical basis and its application.
|
Academic Article
|
Noncanonical electromechanical coupling paths in cardiac hERG potassium channel.
|
Concept
|
Protein Domains
|
Concept
|
Loss of Function Mutation
|
Concept
|
Voltage-Gated Sodium Channels
|
Concept
|
Voltage-Gated Sodium Channel Agonists
|
Concept
|
NAV1.4 Voltage-Gated Sodium Channel
|
Grant
|
Surface Plasmon-coupled Fluorescence Microscope to Study Ion Channel Dynamics
|
Grant
|
ELECTROPHYSIOLOGICAL STUDIES OF VOLTAGE GATED CHANNELS
|
Grant
|
The Electrophysiological Studies of Voltage Gated Channels
|
Grant
|
Charge translocation by the sodium-potassium pump in the giant axon of the Humbol
|
Grant
|
Cell-targeted Gold Nanoparticles for Photo-excitation fo Retinal Ganglion Cells
|
Academic Article
|
A Mechanistic Reinterpretation of Fast Inactivation in Voltage-Gated Na + Channels.
|
Academic Article
|
A Mechanistic Reinterpretation of Fast Inactivation in Voltage-Gated Na+ Channels.
|
Academic Article
|
A mechanistic reinterpretation of fast inactivation in voltage-gated Na+ channels.
|